Filtration of galena preparations

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Filtration of preparations based on vegetable raw materials (herbal preparations), alcohol-containing solutions, preparations based on vegetable oils and syrups

Features of filtration of galenic preparations:

• The need for test filtering to determine materials and filtration ratings for each specific task;
• The maximum possible number of filtration stages for even distribution of the mud load;
• The use of composite materials based on fiberglass and cellulose in the prefiltration stages;
• The need to select the material of filter elements to reduce the sorption of active substances on the surface of the filter.

Filtering elements for filtering galenic preparations

Filter elements of stainless steel brand ECOSTEEL.

To filter galenic preparations, solutions based on vegetable oils, syrups, ointments, gels and other solutions, including viscous, at normal and elevated temperature.

• Filtration rating from 5 to 500 μm;
• Operating temperature up to 230°C;
• All-metal construction;
• The possibility of multiple chemical regenerations and reuse.

Filter elements based on fiberglass and cellulose brands ECOSTEK.

Filtration properties of which are based on high sorption capacity, have high retention in relation to colloidal pollution of various nature.

• The use of fiberglass of different dispersion allows to produce thin cardboard with a thickness of 0.5-0.7   mm with filtration ratings of 0.5, 0.8, 1, 2 and 5   µm;
• Adding various sorbents with both negative and positive electrokinetic potential (so-called zeta-plus, zeta-minus) allows for selective selectivity to individual cultures of microorganisms;
• The ability to multiple washes (5% solution of caustic soda at a temperature of up to 90 °) can significantly increase the service life;
• Elements can withstand any method of sanitary-chemical treatment in accordance with MU-287-113. Sterilization with live steam in a line at 121°C for 45   minutes.

Corrugated film filter elements based on polypropylene films ECOPLEN-PP.

They have a high holding capacity in relation to colloidal and mechanical impurities. Used for coarse preliminary and fine clarifying filtration of protein preparations, culture, bacterial and enzymatic media.

• Filtration rating from 1 to 10 microns;
• High work resource;
• Elements can withstand any method of sanitary-chemical treatment in accordance with U-287-11. Sterilization with live steam in a line at 121°C for 45 minutes.

Filter elements with a fluoroplastic membrane-4 ECOPLEN-F.

Used for control filtration of galenic preparations and alcohol-containing solutions. Elements ECOPLEN-F have a high service life with the possibility of carrying out chemical regenerations using acidic or alkaline solutions, incl. concentrated, unlimited number of sterilization cycles in the line with live steam at a temperature of 134°C.

• Filtration rating 0.5-5   μm;
• Particle retention efficiency – 99.9%;
• Water capacity from 5 to 17 m³/h at a pressure drop of 1   atm;
• Operating temperature up to 130°C;
• The sterilization temperature is 134°C for an unlimited number of cycles.

Filter elements for filtering drugs

Fluoroplast depth filtering elements-4 ECOPLAST-F.

Used for fine clarifying and control filtration of galenic preparations and alcohol-containing solutions.

• Filtration rating from 0.2 to 10 μm;
• Particle retention efficiency – 99%;
• Operating temperature – from -30 to 170°C;
• Chemically inert when filtering any mineral and organic compounds;
• Subject to chemical regeneration and backwash at a pressure drop of up to 6 atm.

Ultrahigh Molecular Weight Polyethylene Depth Filter Elements  
ECOPLAST-PE.

Used to pre-filter galenical preparations, syrups and other pharmaceutical fluids, including viscous.

• Filtration rating of 1-50 μm;
• Particle retention efficiency – 98-99%.
• Operating temperature – from -30 to 100°C;
• Chemically inert when filtering most mineral and organic compounds;
• Subject to chemical regeneration and backwash at a pressure drop of up to 6 atm.

Filter housihgs

Obninsk Filters offers filter housihgs stainless steel AISI 316L, providing performance from 100 l/h to 10 m³/hour.

• Filter housihgs are made in the medical version, with electro-polishing;
• Due to the one-piece construction of the base of the filter housihg, the number of welds is minimized, all surfaces of the filter housihg can be easily processed and polished.

Filtration Installations

Especially for the clarification of herbal preparations, several modifications of the cartridge filtration units have been developed. The pump of installations is made in explosion-proof execution. Installations have a pallet with drain valve, can be additionally equipped with a tank for cleaning the system.

 

Design

Installations are made in two versions:

• With manual engine speed control;
• With automatic engine speed control.

Purpose:

• Installations with automatic control are intended for control filtration of alcohol-containing preparations before bottling;
• For pre-clarification of solutions, a manual control unit is proposed with the ability to work together with a press filter or with a bag (bag) type filter to remove the bulk of large particles.

The proposed equipment will allow you to solve the following tasks:

• Filter system selection;
• Clarification and stabilization of tinctures;
• Clarification of solutions;
• Control filtration of drugs;
• Re-filtering «clean» marriage – tinctures, which precipitated;
• Filtration of small volumes of drugs without significant losses.